Mark Bear

Mark F. Bear, Ph.D.

Principal Investigator

Dr. Mark Bear is a Picower Professor of Neuroscience in The Picower Institute for Learning and Memory and the Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology. He was an Investigator of the Howard Hughes Medical Institute for 22 years from 1994 to 2015, and served as Director of the Picower Institute from 2007 to 2009. Dr. Bear served as Director of The Picower Institute from 2007 to 2009. Prior to moving to MIT in 2003, Dr. Bear was on the faculty of Brown University School of Medicine for 17 years. After receiving his B.S. degree from Duke University, he earned his Ph.D. degree in neurobiology at Brown. He took postdoctoral training from Wolf Singer at the Max Planck Institute for Brain Research in Frankfurt, Germany, and from Leon Cooper at Brown. His laboratory is interested in how the brain is modified by experience. He uses a variety of methods (electrophysiological, biochemical, molecular, behavioral, and anatomical) to examine the synaptic modifications that form the neurobiological basis of learning and memory. His work is particularly focused on understanding developmental plasticity in the visual cortex, as well as other forms of experience-dependent synaptic modification in visual cortex and hippocampus. In recent years Dr. Bear has described novel forms of procedural learning in the visual system, and investigated synaptic function in models of fragile X syndrome and other autism spectrum disorders.

Education

Ph.D. degree, Brown University, 1984

B.Sc. degree, Duke University, 1979

Professional Positions

Picower Professor of Neuroscience, Massachusetts Institute of Technology, 2003 - Present

Investigator, Howard Hughes Medical Institute, 1999 - 2015

Director, The Picower Institute for Learning and Memory, MIT, 2007-2009

Sidney and Dorothy Doctors Fox Professor of Visual Neuroscience, Brown University Medical School, 1996-2003

Associate Investigator, Howard Hughes Medical Institute, 1994-1999

Professor of Neuroscience, Brown University Medical School, 1995-2003

Associate Professor with tenure, Brown University Medical School, 1991-1995

Assistant Professor (tenure track), Brown University Medical School, 1986-1991

Research Assistant Professor, Brown Center for Neural Science, 1985-1986

Max-Planck Fellow with Wolf Singer, Frankfurt, 1984-1985

Significant Memberships

Elected Fellow, American College of Neuropsychopharmacology, 2005

Elected Fellow, American Academy of Arts and Sciences, 2004

Elected Fellow, American Association for the Advancement of Science, 2003

Elected Fellow, Dana Alliance for Brain Initiatives, 1999

Elected Fellow, The Neurosciences Institute, La Jolla, California, 1999

Member, Dana Alliance for Brain Research Executive Committee, 2010 - Present

Member, Institute of Medicine Forum on Neuroscience and Nervous System Disorders, 2009 - Present

Board of Reviewing Editors, Science, 2011-2014

Jury Member, Society for Neuroscience Julius Axelrod Prize, 2009-2011

Jury Member, Antonio Champalimaud Foundation Vision Award, 2007-

Scientific Advisory Board, Brain Research New Zealand, 2015-

Scientific Advisory Board, BioAxone Biosciences, Inc., 2015-

Scientific Advisory Board, Sage Therapeutics, Inc., 2013-2015

Scientific Advisory Board, Mnemosyne Pharmaceutics, Inc., 2011-

Scientific Advisory Board, SynapDx Corp., 2011-

Scientific Advisory Committee, Lieber Institute for Brain Development, Johns Hopkins University, 2011- Present

Scientific Advisory Board, FRAXA Research Foundation, 2009 - Present

Scientific Advisory Panel, Neuroscience Therapeutic Area, Pfizer, Inc, 2008-2010, 2014-

Scientific Advisory Board, The Stanley Center for Psychiatric Research, Broad Institute, MIT, 2007 - Present

Scientific Advisory Board, Seaside Therapeutics, Inc, 2005 - Present

Awards

Beckman-Argyros Vision Award 2018

IPSEN Foundation Neuroscience Prize 2015

Ray Fuller Award, American Society for Pharmacology and Experimental Therapeutics, 2012

Award for Outstanding Contributions to the Study of Metabotropic Glutamate Receptors, 7th International mGluR Meeting, Taormina, Italy, 2011

Pioneer Award, FRAXA Research Foundation, 2011

William and Enid Rosen Award for Outstanding Contributions to Understanding Fragile X Syndrome, National Fragile X Foundation, 2006

Brown University Elizabeth H. Leduc Award for Teaching Excellence, 2000

Brown University Class of 2000 Barrett Hazeltine Citation for Teaching Excellence

Fogarty Senior International Fellowship, 1993

Society for Neuroscience Young Investigator Award, 1993

United States Office of Naval Research Young Investigator Award, 1988

Alfred P. Sloan Award, 1987